TISSUE-SPECIFIC MECHANISMS FOR CCN2/CTGF PERSISTENCE IN FIBROTIC GINGIVA: INTERACTIONS BETWEEN cAMP AND MAPK SIGNALING PATHWAYS, AND PGE2-EP3 RECEPTOR MEDIATED ACTIVATION OF THE c-JUN-N-TERMINAL KINASE
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چکیده
TISSUE-SPECIFIC MECHANISMS FOR CCN2/CTGF PERSISTENCE IN FIBROTIC GINGIVA: INTERACTIONS BETWEEN cAMP AND MAPK SIGNALING PATHWAYS, AND PGE2-EP3 RECEPTOR MEDIATED ACTIVATION OF THE c-JUN-N-TERMINAL KINASE Samuel A. Black Jr., Amitha H. Palamakumbura, Maria Stan and Philip C. Trackman* From the Department of Periodontology and Oral Biology, Division of Oral Biology, Boston University Goldman School of Dental Medicine, Boston, MA 02118 Running title: CCN2/CTGF Persistence in Fibrotic Human Gingiva Address correspondence to: Philip C. Trackman, Ph.D.,Professor, Boston University Goldman School of Dental Medicine, Department of Periodontology and Oral Biology, Division of Oral Biology, 700 Albany Street, Boston, MA 02118, Tel. 617 638-4076; Fax. 617 638 5265, email: [email protected]
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تاریخ انتشار 2007